Structure of PDB 6gmh Chain U

Receptor sequence
>6gmhU (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
GGGGGGGGGG
3D structure
PDB6gmh Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
ChainU
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna U X528 X529 X109 X110
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding
Biological Process
GO:0001711 endodermal cell fate commitment
GO:0006368 transcription elongation by RNA polymerase II
GO:0016055 Wnt signaling pathway
GO:0019827 stem cell population maintenance
GO:0031124 mRNA 3'-end processing
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0016593 Cdc73/Paf1 complex

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External links
PDB RCSB:6gmh, PDBe:6gmh, PDBj:6gmh
PDBsum6gmh
PubMed30135578
UniProtQ8WVC0|LEO1_HUMAN RNA polymerase-associated protein LEO1 (Gene Name=LEO1)

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