Structure of PDB 5xtc Chain U

Receptor sequence
>5xtcU (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
AARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPY
NYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL
3D structure
PDB5xtc Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
ChainU
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PLX U E16 F23 G26 E15 F22 G25
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0009060 aerobic respiration
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function

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Cellular Component
External links
PDB RCSB:5xtc, PDBe:5xtc, PDBj:5xtc
PDBsum5xtc
PubMed28844695
UniProtO95167|NDUA3_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (Gene Name=NDUFA3)

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