Structure of PDB 5xs0 Chain U

Receptor sequence
>5xs0U (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
CFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINL
ANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDV
GYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRS
LNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSC
3D structure
PDB5xs0 Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
ChainU
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna U G58 G59 K102 Y104 E130 G131 K133 S134 L137 G34 G35 K78 Y80 E106 G107 K109 S110 L113 PDBbind-CN: Kd=5.6nM
Gene Ontology
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000730 DNA recombinase assembly
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0045002 double-strand break repair via single-strand annealing
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:5xs0, PDBe:5xs0, PDBj:5xs0
PDBsum5xs0
PubMed30428330
UniProtP43351|RAD52_HUMAN DNA repair protein RAD52 homolog (Gene Name=RAD52)

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