Structure of PDB 5c6h Chain U

Receptor sequence
>5c6hU (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGV
QRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF
GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH
V
3D structure
PDB5c6h Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution
ChainU
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide U Q229 R233 T280 Q59 R63 T110
BS02 peptide U H224 F228 M231 K234 L235 S245 R248 V249 V253 D256 N260 G262 R263 F318 F319 H54 F58 M61 K64 L65 S75 R78 V79 V83 D86 N90 G92 R93 F148 F149
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5c6h, PDBe:5c6h, PDBj:5c6h
PDBsum5c6h
PubMed
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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