Structure of PDB 4u7u Chain U

Receptor sequence
>4u7uU (length=354) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSV
DEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAI
RVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWF
TAVDDLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHML
ATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPS
IQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVR
NNGE
3D structure
PDB4u7u Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
ChainU
Resolution3.003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna U N19 R20 K27 S40 Q42 S43 R46 M166 N19 R20 K27 S40 Q42 S43 R46 M166
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u7u, PDBe:4u7u, PDBj:4u7u
PDBsum4u7u
PubMed25118175
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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