Structure of PDB 3mwi Chain U

Receptor sequence
>3mwiU (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFID
YPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIAL
LKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKENSTDYLY
PEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGG
PLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
3D structure
PDB3mwi The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
ChainU
Resolution2.03 Å
3D
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Enzymatic activity
Enzyme Commision number 3.4.21.73: u-plasminogen activator.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B25 U S190 Q192 S195 V213 W215 G216 G226 V227 S193 Q195 S198 V216 W218 G219 G229 V230
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3mwi, PDBe:3mwi, PDBj:3mwi
PDBsum3mwi
PubMed
UniProtP00749|UROK_HUMAN Urokinase-type plasminogen activator (Gene Name=PLAU)

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