Structure of PDB 3cxc Chain U

Receptor sequence
>3cxcU (length=65) Species: 2238 (Haloarcula marismortui) [Search protein sequence]
TVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELR
KAIARIKTIQGEEGD
3D structure
PDB3cxc Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
ChainU
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna U T1 H4 V5 E7 R9 Q34 P43 G44 R50 K51 A54 R55 K57 T58 E62 T1 H4 V5 E7 R9 Q34 P43 G44 R50 K51 A54 R55 K57 T58 E62 PDBbind-CN: IC50=4.6uM
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:3cxc, PDBe:3cxc, PDBj:3cxc
PDBsum3cxc
PubMed18947996
UniProtP10971|RL29_HALMA Large ribosomal subunit protein uL29 (Gene Name=rpl29)

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