Structure of PDB 8g2z Chain TC

Receptor sequence
>8g2zTC (length=430) Species: 452467 (Tetrahymena thermophila CU428) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPDAFNTFFSETGAG
KHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYT
IGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSV
DYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEAI
YDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNL
VPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPRH
GKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQP
PTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYV
GEGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB8g2z Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
ChainTC
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP TC G10 Q11 G12 Q15 D98 N101 S140 G142 G143 G144 T145 I171 N206 Y224 G10 Q11 G12 Q15 D89 N92 S131 G133 G134 G135 T136 I162 N197 Y215
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g2z, PDBe:8g2z, PDBj:8g2z
PDBsum8g2z
PubMed37061538
UniProtP41351|TBA_TETTH Tubulin alpha chain

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