Structure of PDB 8s8h Chain T

Receptor sequence

>8s8hT (length=143) Species: 284590 (Kluyveromyces lactis NRRL Y-1140)

PGVSVRDVPAQDFINNYASFLQRQGKLEVPGYVDIVKTSAGNELPPQDSE
GWFYKRAASVARHIYLRKQVGVGKLNKLYGGAKNRGVRPHKHVDASGSIN
RKVLQSLEKLGVVEISPKGGRRISDNGLRDLDRIAAATLEDEE

3D structure

• PDB: 8s8h Structural basis of AUC codon discrimination during translation initiation in yeast.
• Chain: T
• Resolution: 4.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	P2 R7 A11 Q12 Y33 K38 T39 N43 E44 P47 Q48 R57 S60 R63 R68 K69 G72 V73 G74 K75 K78 Y80 G82 A83 K84 N85 R86 G87 V88 R89 P90 H91 K92 H93 S97 S99 R102 Q106 R122 D126 L129 R130 D133	P1 R6 A10 Q11 Y32 K37 T38 N42 E43 P46 Q47 R56 S59 R62 R67 K68 G71 V72 G73 K74 K77 Y79 G81 A82 K83 N84 R85 G86 V87 R88 P89 H90 K91 H92 S96 S98 R101 Q105 R121 D125 L128 R129 D132

External links

• PDB: RCSB:8s8h, PDBe:8s8h, PDBj:8s8h
• PDBsum: 8s8h
• PubMed: 39193907
• UniProt: Q6CXM0