Structure of PDB 8rw1 Chain T

Receptor sequence

>8rw1T (length=143) Species: 284590 (Kluyveromyces lactis NRRL Y-1140)

PGVSVRDVPAQDFINNYASFLQRQGKLEVPGYVDIVKTSAGNELPPQDSE
GWFYKRAASVARHIYLRKQVGVGKLNKLYGGAKNRGVRPHKHVDASGSIN
RKVLQSLEKLGVVEISPKGGRRISDNGLRDLDRIAAATLEDEE

3D structure

• PDB: 8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.
• Chain: T
• Resolution: 3.35 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	P2 G3 R7 Q12 K38 N43 P47 Q48 K56 R57 S60 R63 H64 R68 K69 G72 V73 G74 K75 K78 L79 Y80 G82 A83 K84 R86 G87 V88 R89 P90 H91 K92 H93 S97 G98 S99 R102 Q106 G121 R122 L129 R130 D133	P1 G2 R6 Q11 K37 N42 P46 Q47 K55 R56 S59 R62 H63 R67 K68 G71 V72 G73 K74 K77 L78 Y79 G81 A82 K83 R85 G86 V87 R88 P89 H90 K91 H92 S96 G97 S98 R101 Q105 G120 R121 L128 R129 D132

External links

• PDB: RCSB:8rw1, PDBe:8rw1, PDBj:8rw1
• PDBsum: 8rw1
• PubMed: 39193907
• UniProt: Q6CXM0