Structure of PDB 8imy Chain T

Receptor sequence
>8imyT (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
PPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGVSHYRLFPKALG
QLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTVTDVD
KSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYA
VLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRP
VCRNARCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPL
ASESRVYVDITTYNQDNETLEVHPPPTTTYQDVILGTRKTYAIYDLLDTA
MINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSGYGLQKGELSTLLYN
THPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQDRLQ
PHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSAL
VPSMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSM
PYNVICLTCTVVAVCYGSFYNLLTRTFHIE
3D structure
PDB8imy Structures of substrates- and products-bound glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis
ChainT
Resolution3.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 81Q T D521 S523 M524 N527 D497 S499 M500 N503
BS02 PA1 T D521 S523 D497 S499
Gene Ontology
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0008218 bioluminescence
GO:0016255 attachment of GPI anchor to protein
Cellular Component
GO:0042765 GPI-anchor transamidase complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8imy, PDBe:8imy, PDBj:8imy
PDBsum8imy
PubMed37684232
UniProtQ969N2|PIGT_HUMAN GPI transamidase component PIG-T (Gene Name=PIGT)

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