Structure of PDB 7uck Chain T

Receptor sequence

>7uckT (length=159) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKG
MPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKS
RDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELL
EPIPYEFMA

3D structure

PDB

7uck Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	N3 T4 K5 G6 K7 R8 R9 G10 R12 Y13 S16 R17 F19 H22 G23 K35 D41 G46 Q49 G51 H54 K55 Y57 H58 G59 K60 T61 T68 Q69 H70 K78 V80 K81 L85 K87 R88 R92 S101 R102 S104 F105 V109 K116 K120 W125 V126 L128 K129 R130 F140	N2 T3 K4 G5 K6 R7 R8 G9 R11 Y12 S15 R16 F18 H21 G22 K34 D40 G45 Q48 G50 H53 K54 Y56 H57 G58 K59 T60 T67 Q68 H69 K77 V79 K80 L84 K86 R87 R91 S100 R101 S103 F104 V108 K115 K119 W124 V125 L127 K128 R129 F139
BS02	rna	T	L27 A28	L26 A27

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7uck, PDBe:7uck, PDBj:7uck
PDBsum	7uck
PubMed	35679869
UniProt	G1SHQ2\|RL21_RABIT Large ribosomal subunit protein eL21 (Gene Name=RPL21)

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