Structure of PDB 7pwg Chain T

Receptor sequence

>7pwgT (length=153) Species: 184922 (Giardia lamblia ATCC 50803) [Search protein sequence]

THSQGYRCKTRYCFARKFRRHGMANLTTYNRVYKLGQYVNIKVNGAYHKG
MPHRYYNGRTGTIFNIGPRALGVQIQKRVRGRIMLKRINVRLEHVHPSDC
RKNHLERVAANDAARRLAGQPVPCLKRQNALPRAAHVVSIASAIDITPLK
YDG

3D structure

PDB

7pwg Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.

Chain

Resolution

2.75 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	T2 H3 S4 Q5 G6 Y7 R8 C9 R12 R17 F19 H22 K35 Y39 K43 A47 H49 H54 R55 G59 R60 T61 R70 A71 Q77 K78 V80 R83 M85 K87 R88 R92 C101 R102 H105 R108 V109 N112 R116 L129 K130 R131 N133	T1 H2 S3 Q4 G5 Y6 R7 C8 R11 R16 F18 H21 K34 Y38 K42 A46 H48 H53 R54 G58 R59 T60 R69 A70 Q76 K77 V79 R82 M84 K86 R87 R91 C100 R101 H104 R107 V108 N111 R115 L125 K126 R127 N129
BS02	rna	T	R21 N26 T28	R20 N25 T27

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7pwg, PDBe:7pwg, PDBj:7pwg
PDBsum	7pwg
PubMed	35100413
UniProt	A8B2Q4

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