Structure of PDB 7oic Chain T

Receptor sequence

>7oicT (length=166) Species: 9606 (Homo sapiens) [Search protein sequence]

ISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRG
MSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAEST
SGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEPPKTAVAHA
KEYIQQLRSRTIVHTL

3D structure

PDB

7oic A distinct assembly pathway of the human 39S late pre-mitoribosome.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	I47 S48 K50 W51 K54 R78 K81 Y82 S83 K86 W88 R95 D110 K111 K112 T146 R149 G150 Q151 R157 Y158 H159 G160 R161 G162 R163 F164 I166 M167 E168 K169 H173 F175 S205 R206 T207 H210	I1 S2 K4 W5 K8 R32 K35 Y36 S37 K40 W42 R49 D64 K65 K66 T100 R103 G104 Q105 R111 Y112 H113 G114 R115 G116 R117 F118 I120 M121 E122 K123 H127 F129 S159 R160 T161 H164

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation
GO:0032543	mitochondrial translation

	Cellular Component
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005762	mitochondrial large ribosomal subunit
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7oic, PDBe:7oic, PDBj:7oic
PDBsum	7oic
PubMed	34315873
UniProt	Q9NWU5\|RM22_HUMAN Large ribosomal subunit protein uL22m (Gene Name=MRPL22)

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