Structure of PDB 7md5 Chain T
Receptor sequence
>7md5T (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
7md5
Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Chain
T
Resolution
5.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
T
F1801 N1803 Q1804 H1805 L1811 V1818 C1819 R1822 G1823 F1824 F1825
F1 N3 Q4 H5 L11 V18 C19 R22 G23 F24 F25
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
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Cellular Component
External links
PDB
RCSB:7md5
,
PDBe:7md5
,
PDBj:7md5
PDBsum
7md5
PubMed
35177603
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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