Structure of PDB 7md5 Chain T

Receptor sequence
>7md5T (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB7md5 Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
ChainT
Resolution5.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide T F1801 N1803 Q1804 H1805 L1811 V1818 C1819 R1822 G1823 F1824 F1825 F1 N3 Q4 H5 L11 V18 C19 R22 G23 F24 F25
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:7md5, PDBe:7md5, PDBj:7md5
PDBsum7md5
PubMed35177603
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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