Structure of PDB 7kd6 Chain T
Receptor sequence
>7kd6T (length=47) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFRRGIVEQCCHSICSLEQLENYC
3D structure
PDB
7kd6
Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Chain
T
Resolution
2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
T
G8 V12 F24 F25 R36 G37 I38 V39 E40 E53 N54 Y55 C56
G8 V12 F24 F25 R27 G28 I29 V30 E31 E44 N45 Y46 C47
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
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Cellular Component
External links
PDB
RCSB:7kd6
,
PDBe:7kd6
,
PDBj:7kd6
PDBsum
7kd6
PubMed
36181268
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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