Structure of PDB 7kd6 Chain T

Receptor sequence
>7kd6T (length=47) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFRRGIVEQCCHSICSLEQLENYC
3D structure
PDB7kd6 Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
ChainT
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide T G8 V12 F24 F25 R36 G37 I38 V39 E40 E53 N54 Y55 C56 G8 V12 F24 F25 R27 G28 I29 V30 E31 E44 N45 Y46 C47
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:7kd6, PDBe:7kd6, PDBj:7kd6
PDBsum7kd6
PubMed36181268
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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