Structure of PDB 6w6l Chain T

Receptor sequence

>6w6lT (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]

MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQ
LKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDL
TTAGAVTQCYRDMGARHRARAHSIQIMKVEEIAASKCRRPAVKQFHDSKI
KFPLPHRVLRRQHKPRFTTKRPNTF

3D structure

PDB

6w6l An ER translocon for multi-pass membrane protein biogenesis.

Chain

Resolution

3.84 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	S42 Y46 S49 K52 K53 K55 K56 S57 H122	S42 Y46 S49 K52 K53 K55 K56 S57 H122
BS02	rna	T	K2 A3 S4 G5 F68 K70 S86 R87 H91 M93 R95 R98 R111 G114 A115 R116 H117 R118 R139 H146 D147 S148 H156 L159 Q162 H163 R166 T168 K170 R171 P172 N173 T174 F175	K2 A3 S4 G5 F68 K70 S86 R87 H91 M93 R95 R98 R111 G114 A115 R116 H117 R118 R139 H146 D147 S148 H156 L159 Q162 H163 R166 T168 K170 R171 P172 N173 T174 F175

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:6w6l, PDBe:6w6l, PDBj:6w6l
PDBsum	6w6l
PubMed	32820719
UniProt	Q02543\|RL18A_HUMAN Large ribosomal subunit protein eL20 (Gene Name=RPL18A)

[Back to BioLiP]