Structure of PDB 6r6g Chain T

Receptor sequence

>6r6gT (length=159) Species: 9986 (Oryctolagus cuniculus)

TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKG
MPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKS
RDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELL
EPIPYEFMA

3D structure

• PDB: 6r6g Structural and mutational analysis of the ribosome-arresting human XBP1u.
• Chain: T
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	T	T2 N3 T4 K5 G6 K7 R8 R9 G10 R12 Y13 M14 S16 R17 F19 H22 G23 I39 D41 K43 G46 T47 Q49 K50 G51 H54 K55 H58 K60 T61 T68 Q69 H70 K78 V80 L85 K87 R92 K100 S101 S104 F105 R108 V109 K116 W125 L128 K129 R130 P132 F140	T1 N2 T3 K4 G5 K6 R7 R8 G9 R11 Y12 M13 S15 R16 F18 H21 G22 I38 D40 K42 G45 T46 Q48 K49 G50 H53 K54 H57 K59 T60 T67 Q68 H69 K77 V79 L84 K86 R91 K99 S100 S103 F104 R107 V108 K115 W124 L127 K128 R129 P131 F139
BS02	rna	T	R20 L27 A28	R19 L26 A27

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6r6g, PDBe:6r6g, PDBj:6r6g
• PDBsum: 6r6g
• PubMed: 31246176
• UniProt: G1SHQ2|RL21_RABIT Large ribosomal subunit protein eL21 (Gene Name=RPL21)