Structure of PDB 5nrl Chain T

Receptor sequence
>5nrlT (length=462) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFPDTKLPR
SSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINFER
KLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDL
DLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDE
KYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDF
EHSYCRGSLRSEAKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNF
VYSEYKLHRYLKYLNDEFSRTRSFVERKLAFTANERMAEMDILTQKYEAP
AYDSTEKEGAEQVDMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFN
EERHIYHLRCLGIEPSSVFKGITKIKEAQELWKNMQELELEEEDEEGNVM
SKKVYDELKKQG
3D structure
PDB5nrl Structure of a pre-catalytic spliceosome.
ChainT
Resolution7.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna T Y409 W410 R419 R434 Y367 W368 R377 R392
BS02 rna T W410 L411 L414 W368 L369 L372
BS03 ZN T C285 H298 H304 C271 H284 H290
BS04 ZN T C423 C426 H440 H446 C381 C384 H398 H404
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nrl, PDBe:5nrl, PDBj:5nrl
PDBsum5nrl
PubMed28530653
UniProtP19736|PRP9_YEAST Pre-mRNA-splicing factor PRP9 (Gene Name=PRP9)

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