Structure of PDB 5nif Chain T

Receptor sequence
>5nifT (length=232) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
RNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRN
ADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRK
LAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGN
VTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLR
DESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI
3D structure
PDB5nif Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome - insights into the enzyme activation mechanism.
ChainT
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide T A28 Q31 G32 S33 R51 K62 A75 G76 A26 Q29 G30 S31 R49 K60 A73 G74
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex
GO:0034515 proteasome storage granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nif, PDBe:5nif, PDBj:5nif
PDBsum5nif
PubMed28733623
UniProtP40302|PSA6_YEAST Proteasome subunit alpha type-6 (Gene Name=PRE5)

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