Structure of PDB 4u7u Chain T

Receptor sequence
>4u7uT (length=360) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSV
DEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAI
RVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWF
TAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEI
ATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKA
KDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDPITAQVKQMPTLEQ
LKSWVRNNGE
3D structure
PDB4u7u Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
ChainT
Resolution3.003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna T N19 R20 D21 D22 K27 S40 Q42 S43 R46 M166 F200 T201 V203 G210 L214 K266 N19 R20 D21 D22 K27 S40 Q42 S43 R46 M166 F200 T201 V203 G210 L214 K266
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u7u, PDBe:4u7u, PDBj:4u7u
PDBsum4u7u
PubMed25118175
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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