Structure of PDB 4tvx Chain T

Receptor sequence
>4tvxT (length=219) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD
TSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS
HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS
CPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEP
MITLPRQFASREWYVIKGG
3D structure
PDB4tvx Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
ChainT
Resolution3.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna T G17 Q18 P19 T20 R25 S34 G38 L39 G41 A42 I46 R48 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208 G17 Q18 P19 T20 R25 S34 G38 L39 G41 A42 I46 R48 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4tvx, PDBe:4tvx, PDBj:4tvx
PDBsum4tvx
PubMed25103409
UniProtQ46898|CAS5_ECOLI CRISPR system Cascade subunit CasD (Gene Name=casD)

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