Structure of PDB 4csf Chain T

Receptor sequence
>4csfT (length=250) Species: 11590 (Toscana virus) [Search protein sequence]
DENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAKG
RDWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGNP
GRDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMH
PSFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATF
EKPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKVG
3D structure
PDB4csf Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
ChainT
Resolution2.598 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna T Y32 K204 P205 Y30 K202 P203 PDBbind-CN: Kd=260nM
BS02 rna T K79 T185 I186 K77 T183 I184 PDBbind-CN: Kd=260nM
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177 host cell Golgi apparatus
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4csf, PDBe:4csf, PDBj:4csf
PDBsum4csf
PubMed24688060
UniProtP21701|NCAP_TOSV Nucleoprotein (Gene Name=N)

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