Structure of PDB 2kfx Chain T

Receptor sequence
>2kfxT (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDS
3D structure
PDB2kfx Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C.
ChainT
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA T D65 D67 S69 T71 E76 D65 D67 S69 T71 E76
BS02 WW7 T F27 I36 L41 M45 V72 F77 M80 M81 F27 I36 L41 M45 V72 F77 M80 M81 PDBbind-CN: -logKd/Ki=4.00,Kd=100uM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2kfx, PDBe:2kfx, PDBj:2kfx
PDBsum2kfx
PubMed19419198
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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