Structure of PDB 8xt0 Chain Sm

Receptor sequence
>8xt0Sm (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
ATPSLRGRLARFGNPRKPVLKPNKPLILANRVGERRREKGEATCITEMSV
MMACWKQNEFRDDACRKEIQGFLDCAARAQEARKMRSIQETLGESGSLLP
NKLNKLLQRFPNKPYL
3D structure
PDB8xt0 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSm
Resolution3.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Sm P4 R9 A11 R12 R17 K18 P19 V20 K22 N24 K25 G34 R36 R37 R38 R84 K85 S98 L104 Q109 R110 P3 R8 A10 R11 R16 K17 P18 V19 K21 N23 K24 G33 R35 R36 R37 R83 K84 S97 L103 Q108 R109
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xt0, PDBe:8xt0, PDBj:8xt0
PDBsum8xt0
PubMed38942792
UniProtQ96BP2|CHCH1_HUMAN Small ribosomal subunit protein mS37 (Gene Name=CHCHD1)

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