Structure of PDB 8k2a Chain Si

Receptor sequence
>8k2aSi (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
SEYAFRMSRLSARLFGEVTRPTNSKSMKVVKLFSELPLAKKKETYDWYPN
HHTYAELMQTLRFLGLYRDEHQDFMDEQKRLKKLRG
3D structure
PDB8k2a Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSi
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Si K32 H56 F67 H75 F78 Q82 R89 K28 H52 F63 H71 F74 Q78 R85
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k2a, PDBe:8k2a, PDBj:8k2a
PDBsum8k2a
PubMed38942792
UniProtQ9Y291|RT33_HUMAN Small ribosomal subunit protein mS33 (Gene Name=MRPS33)

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