Structure of PDB 8rxh Chain Sh

Receptor sequence
>8rxhSh (length=96) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]
NSSCVFVSPIFRPSTTKAQVMELFAGVKVQRLRMYRQNFAYAYLDSPAAA
KKFVEEKNGTEFRGHTLRVALSARSLEKLRARQEAANVVIAAHRHY
3D structure
PDB8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
ChainSh
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna Sh F139 P142 F144 R145 P146 S147 R164 R166 Y168 R169 Q170 Y174 R196 H198 A203 S205 A206 R215 Q216 I223 H226 R227 F6 P9 F11 R12 P13 S14 R31 R33 Y35 R36 Q37 Y41 R63 H65 A70 S72 A73 R82 Q83 I90 H93 R94
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8rxh, PDBe:8rxh, PDBj:8rxh
PDBsum8rxh
PubMed38722744
UniProtQ4Q5K7

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