Structure of PDB 8rxh Chain Sg

Receptor sequence
>8rxhSg (length=303) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]
MNYEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSV
DSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQ
RKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHE
DWVSSICFSPSPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVS
PDGSLCASGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVA
TERSLSVYDLESKAVIAELTPKPSECISIAWSADGNTLYSGHKDNLIRVW
SIS
3D structure
PDB8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
ChainSg
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Sg R11 T65 R11 T65
Gene Ontology
Molecular Function
GO:0005080 protein kinase C binding
GO:0016301 kinase activity
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0006417 regulation of translation
GO:0016310 phosphorylation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxh, PDBe:8rxh, PDBj:8rxh
PDBsum8rxh
PubMed38722744
UniProtQ4Q7Y7

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