Structure of PDB 8xsy Chain Sd
Receptor sequence
>8xsySd (length=55) Species:
9606
(Homo sapiens) [
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GHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIG
FIKLD
3D structure
PDB
8xsy
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Chain
Sd
Resolution
3.0 Å
3D
structure
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Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
Sd
G2 H3 L6 Y7 H10 P11 R12 K13 F14 Q16 G17 S18 R19 R22 C24 N26 R27 H28 G29 L30 I31 R32 K33 Y34 R40 Q41 R44 D56
G1 H2 L5 Y6 H9 P10 R11 K12 F13 Q15 G16 S17 R18 R21 C23 N25 R26 H27 G28 L29 I30 R31 K32 Y33 R39 Q40 R43 D55
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
GO:0008270
zinc ion binding
GO:0046872
metal ion binding
Biological Process
GO:0002181
cytoplasmic translation
GO:0006412
translation
Cellular Component
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
GO:0005783
endoplasmic reticulum
GO:0005791
rough endoplasmic reticulum
GO:0005829
cytosol
GO:0005840
ribosome
GO:0005925
focal adhesion
GO:0015935
small ribosomal subunit
GO:0022626
cytosolic ribosome
GO:0022627
cytosolic small ribosomal subunit
GO:0070062
extracellular exosome
GO:0098556
cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904
ribonucleoprotein complex
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:8xsy
,
PDBe:8xsy
,
PDBj:8xsy
PDBsum
8xsy
PubMed
38942792
UniProt
P62273
|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)
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