Structure of PDB 8g5y Chain Sd

Receptor sequence

>8g5ySd (length=55) Species: 9606 (Homo sapiens)

GHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIG
FIKLD

3D structure

• PDB: 8g5y mRNA decoding in human is kinetically and structurally distinct from bacteria.
• Chain: Sd
• Resolution: 2.29 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Sd	G2 H3 L6 Y7 W8 S9 H10 P11 R12 K13 F14 Q16 G17 S18 R19 R22 C24 N26 H28 L30 I31 R32 K33 Y34 R40 Q41 R44 K54 L55 D56	G1 H2 L5 Y6 W7 S8 H9 P10 R11 K12 F13 Q15 G16 S17 R18 R21 C23 N25 H27 L29 I30 R31 K32 Y33 R39 Q40 R43 K53 L54 D55
BS02	ZN	Sd	C21 C24 C39 C42	C20 C23 C38 C41
BS03	MG	Sd	N26 H28 C39 Q41	N25 H27 C38 Q40

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0046872 metal ion binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005654 nucleoplasm
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0005791 rough endoplasmic reticulum
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0005925 focal adhesion
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:0070062 extracellular exosome
• GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8g5y, PDBe:8g5y, PDBj:8g5y
• PDBsum: 8g5y
• PubMed: 37020024
• UniProt: P62273|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)