Structure of PDB 6zm7 Chain Sd

Receptor sequence

>6zm7Sd (length=55) Species: 9606 (Homo sapiens) [Search protein sequence]

GHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIG
FIKLD

3D structure

PDB

6zm7 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.

Chain

Resolution

2.7 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Sd	G2 H3 L6 Y7 W8 S9 H10 P11 R12 K13 F14 G15 Q16 G17 R19 R22 C24 N26 R27 H28 G29 L30 I31 R32 K33 Y34 R40 Q41 R44 K54 L55 D56	G1 H2 L5 Y6 W7 S8 H9 P10 R11 K12 F13 G14 Q15 G16 R18 R21 C23 N25 R26 H27 G28 L29 I30 R31 K32 Y33 R39 Q40 R43 K53 L54 D55
BS02	ZN	Sd	C21 C39 C42	C20 C38 C41

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0015935	small ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0070062	extracellular exosome
GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6zm7, PDBe:6zm7, PDBj:6zm7
PDBsum	6zm7
PubMed	32680882
UniProt	P62273\|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)