Structure of PDB 5lks Chain Sd

Receptor sequence
>5lksSd (length=53) Species: 9606 (Homo sapiens) [Search protein sequence]
QQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFI
KLD
3D structure
PDB5lks Structure-function insights reveal the human ribosome as a cancer target for antibiotics.
ChainSd
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Sd Q4 Q5 W8 S9 H10 P11 R12 K13 F14 Q16 R19 N26 H28 L30 I31 R32 Y34 R40 Q41 R44 L55 D56 Q1 Q2 W5 S6 H7 P8 R9 K10 F11 Q13 R16 N23 H25 L27 I28 R29 Y31 R37 Q38 R41 L52 D53
BS02 ZN Sd C24 C39 C42 C21 C36 C39
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular exosome
GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lks, PDBe:5lks, PDBj:5lks
PDBsum5lks
PubMed27665925
UniProtP62273|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)

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