Structure of PDB 8xxl Chain SZ

Receptor sequence
>8xxlSZ (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]
RDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQE
LLSKGLIKLVSKHRAQVIYTRNTKG
3D structure
PDB8xxl Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
ChainSZ
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SZ K43 L44 N46 R80 G81 S82 R85 K102 H103 R104 K3 L4 N6 R40 G41 S42 R45 K62 H63 R64
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0014069 postsynaptic density
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xxl, PDBe:8xxl, PDBj:8xxl
PDBsum8xxl
PubMed38641729
UniProtP62851|RS25_HUMAN Small ribosomal subunit protein eS25 (Gene Name=RPS25)

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