Structure of PDB 8k2a Chain SZ

Receptor sequence
>8k2aSZ (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
KNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAER
TVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEICAVVLRQLSPHKYYFL
VGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL
3D structure
PDB8k2a Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSZ
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SZ K36 N37 R38 A39 R41 R43 V44 H60 H64 R65 K1 N2 R3 A4 R6 R8 V9 H25 H29 R30
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8k2a, PDBe:8k2a, PDBj:8k2a
PDBsum8k2a
PubMed38942792
UniProtQ96EL2|RT24_HUMAN Small ribosomal subunit protein uS3m (Gene Name=MRPS24)

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