Structure of PDB 8fkx Chain SZ

Receptor sequence
>8fkxSZ (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
PKAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQ
NLAEMGLAVDPNRAVPLRLVRKPYVLNDLEAEASLPEKKGNTLSRDLIDY
VRYMVENHGEDYKAMARDEKNYYQDTPKQIRSKINVYKRFYPAEWQDFLD
SLQKRKMEVE
3D structure
PDB8fkx Principles of human pre-60 S biogenesis.
ChainSZ
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SZ P2 K3 K5 K7 R9 F13 R19 K20 R21 R27 A31 R33 H41 H45 A46 S48 R50 K107 N109 S112 R113 T144 K146 Q147 R149 V154 R157 F158 P1 K2 K4 K6 R8 F12 R18 K19 R20 R26 A30 R32 H40 H44 A45 S47 R49 K89 N91 S94 R95 T126 K128 Q129 R131 V136 R139 F140
Gene Ontology
Biological Process
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0043231 intracellular membrane-bounded organelle

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Cellular Component
External links
PDB RCSB:8fkx, PDBe:8fkx, PDBj:8fkx
PDBsum8fkx
PubMed37410842
UniProtQ9Y3C1|NOP16_HUMAN Nucleolar protein 16 (Gene Name=NOP16)

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