Structure of PDB 8fkv Chain SZ

Receptor sequence
>8fkvSZ (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
PKAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQ
NLAEMGLAVDPNRAVPLRLVRKPYVLNDLEAEASLPEKKGNTLSRDLIDY
VRYMVENHGEDYKAMARDEKNYYQDTPKQIRSKINVYKRFYPAEWQDFLD
SLQKRKMEVE
3D structure
PDB8fkv Principles of human pre-60 S biogenesis.
ChainSZ
Resolution2.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SZ T8 S16 K29 T7 S15 K28
BS02 rna SZ P2 K5 R9 R19 K20 R21 R27 R28 A31 R33 H41 H45 A46 S48 R50 K107 N109 S112 D114 T144 Q147 V154 R157 F158 P1 K4 R8 R18 K19 R20 R26 R27 A30 R32 H40 H44 A45 S47 R49 K89 N91 S94 D96 T126 Q129 V136 R139 F140
Gene Ontology
Biological Process
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0043231 intracellular membrane-bounded organelle

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Cellular Component
External links
PDB RCSB:8fkv, PDBe:8fkv, PDBj:8fkv
PDBsum8fkv
PubMed37410842
UniProtQ9Y3C1|NOP16_HUMAN Nucleolar protein 16 (Gene Name=NOP16)

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