Structure of PDB 8fkx Chain SU

Receptor sequence
>8fkxSU (length=552) Species: 9606 (Homo sapiens) [Search protein sequence]
IEEHLIERKKKLQEKKMHIAALASAILSDPENNIKKLKELRSMLMEQDPD
VAVTVRKLVIVSLMELFKDITPSYKIRKETQKLREFEEGLVSQYKFYLEN
LEQMVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNN
IIVLIVPLMNDMSKLISEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKG
RNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKLERELREAEASESTEK
KLKLHTETLNIVFVTYFRILKKAQRSPLLPAVLEGLAKFAHLINVEFFDD
LLVVLHTLIESGDLSYQESLHCVQTAFHILSGQGDVLNIDPLKFYTHLYK
TLFKLHAGATNEGVEIVLQCLDVMLTKRRKQVSQQRALAFIKRLCTLALH
VLPNSSIGILATTRILMHTFPKTDLLLDSESQGSGVFLPELDEPEYCNAQ
NTALWELHALRRHYHPIVQRFAAHLIAGAPSEGSGALKPELSRRSATELF
EAYSMAEMTFNPPVESSNPKIKGKFLQGDSFLNEDLNQLIKRYSSEVATE
SP
3D structure
PDB8fkx Principles of human pre-60 S biogenesis.
ChainSU
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG SU L661 D664 L425 D428
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0003723 RNA binding
Biological Process
GO:0006270 DNA replication initiation
GO:0045444 fat cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0016607 nuclear speck

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fkx, PDBe:8fkx, PDBj:8fkx
PDBsum8fkx
PubMed37410842
UniProtQ8WTT2|NOC3L_HUMAN Nucleolar complex protein 3 homolog (Gene Name=NOC3L)

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