Structure of PDB 8rxh Chain ST

Receptor sequence

>8rxhST (length=143) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]

MVRMHGNGRGKASSALPYRRTPPAWLKIASRNVVKMVCKSSRKGMMPSQI
GMELRDSMGIAQVKNVTGRKILRILKHNGLAPEIPEDLYFLVKRATQMRK
HLERHTTDRDTKYRLILVESRIHRLARYYKRVKQLPPTWKYES

3D structure

PDB

8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.

Chain

Resolution

2.93 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	ST	W139 K140	W139 K140
BS02	rna	ST	M1 V2 R3 M4 H5 G8 R9 G10 K11 A12 S14 A15 L16 P17 R20 P47 S48 Q49 M52 R55 A61 Q62 T67 G68 R69 K70 I71 L72 R73 H77 D87 F90 R94 Q97 M98 H101 H105 T107 D108 R109 D110 Y113 R114 L117 S120 R121 R124 Y128 V132 K133 Q134	M1 V2 R3 M4 H5 G8 R9 G10 K11 A12 S14 A15 L16 P17 R20 P47 S48 Q49 M52 R55 A61 Q62 T67 G68 R69 K70 I71 L72 R73 H77 D87 F90 R94 Q97 M98 H101 H105 T107 D108 R109 D110 Y113 R114 L117 S120 R121 R124 Y128 V132 K133 Q134

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0070181	small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0035869	ciliary transition zone
GO:1990904	ribonucleoprotein complex

External links