Structure of PDB 5wlc Chain ST

Receptor sequence

>5wlcST (length=599) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]

QLKNLKAALKAREKKKAIAEIREEFNPFEIKAARNKRIAVGKPGISKQIG
EEQRKRAFEARKMMKNKRGGVIDKRAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAKEKLGKFTAVLLRHIIFLSNQNYLKNVQSFKRT
QNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGDLVFF
SIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVS
QYQRISKRYIPEVVYFFQKILLTFIVEPLDFENIRLDSYELGLPLDVDFT
KKRSTIIPLHTLSTMDTEAHPVDQCVSVLLNVMESLDATISTVWKSLPAF
NEIILPIQQLLSAYTSKYSDFEKPRNILNKVEKLTKFTEHIPLALQNHKP
VSIPTHAPKYEENFNPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRK
DAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKYERERKLR

3D structure

PDB

5wlc The complete structure of the small-subunit processome.

Chain

Resolution

3.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	ST	K61 A63 R64 K66 G82 K83 P84 S87 X206 X208 X209 X213 X216 X415 X416 D729 P730 R734 K745 K749 F750 K753 H778 A782 H783 N786 T790 R801 R803	K31 A33 R34 K36 G41 K42 P43 S46 X81 X83 X84 X88 X91 X214 X215 D522 P523 R527 K538 K542 F543 K546 H571 A575 H576 N579 T583 R594 R596
BS02	rna	ST	T790 G793	T583 G586

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0034511	U3 snoRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0030490	maturation of SSU-rRNA
GO:0042254	ribosome biogenesis
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0030686	90S preribosome
GO:0030688	preribosome, small subunit precursor
GO:0030692	Noc4p-Nop14p complex
GO:0032040	small-subunit processome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum	5wlc
PubMed	28945246
UniProt	Q99207\|NOP14_YEAST Nucleolar complex protein 14 (Gene Name=NOP14)

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