Structure of PDB 7qvp Chain SS

Receptor sequence

>7qvpSS (length=141) Species: 9606 (Homo sapiens)

IPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTK
RAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLD
NKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRT

3D structure

• PDB: 7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
• Chain: SS
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	SS	F28 K34 G35 V36 G37 R38 R39 Y40 R55 W82 F83 N85 R86 Q87 K88 D110 H120 R121 R124 L129 R130 V131 R132 G133 Q134 H135 T136 K137 T138 G140 R141 G143 T145	F24 K30 G31 V32 G33 R34 R35 Y36 R51 W78 F79 N81 R82 Q83 K84 D106 H116 R117 R120 L125 R126 V127 R128 G129 Q130 H131 T132 K133 T134 G136 R137 G139 T141

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qvp, PDBe:7qvp, PDBj:7qvp
• PDBsum: 7qvp
• PubMed: 36302773
• UniProt: H0WTR0