Structure of PDB 7nrc Chain SR

Receptor sequence

>7nrcSR (length=216) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

GWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNI
KPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAK
LSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPA
VKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQ
PLPVSPLDIYSDEASA

3D structure

PDB

7nrc Structure of Gcn1 bound to stalled and colliding 80S ribosomes.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	SR	V86 Q87 K88 Q89 T90 R91 A92 G93 Q94 R95 K99 T158 T159 K161 C162 G163 S164 R168 V179 A180 S181 Y197 T198 S200 N201 K203 T204 R205 T206 N209 K212	V53 Q54 K55 Q56 T57 R58 A59 G60 Q61 R62 K66 T125 T126 K128 C129 G130 S131 R135 V146 A147 S148 Y164 T165 S167 N168 K170 T171 R172 T173 N176 K179

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7nrc, PDBe:7nrc, PDBj:7nrc
PDBsum	7nrc
PubMed	33790014
UniProt	P25443\|RS2_YEAST Small ribosomal subunit protein uS5 (Gene Name=RPS2)

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