Structure of PDB 7zjw Chain SP

Receptor sequence

>7zjwSP (length=262) Species: 9986 (Oryctolagus cuniculus)

ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNR
LKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRL
IYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPD
PLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERH
PGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEE
RDKRLAAKQSSG

3D structure

• PDB: 7zjw Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
• Chain: SP
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	SP	R3 G4 K7 H8 K10 V12 K16 M19 K22 L23 T24 G25 V26 F27 P29 T33 G34 K37 R49 T57 K62 K63 M66 Q67 K75 R77 K106 R108 K128 V131 G132 T133 K134 V140 A144 R145 T146 R148 K155 G186 A187 H201 A219 R221 R240	R2 G3 K6 H7 K9 V11 K15 M18 K21 L22 T23 G24 V25 F26 P28 T32 G33 K36 R48 T56 K61 K62 M65 Q66 K74 R76 K105 R107 K127 V130 G131 T132 K133 V139 A143 R144 T145 R147 K154 G185 A186 H200 A218 R220 R239

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:0032040 small-subunit processome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7zjw, PDBe:7zjw, PDBj:7zjw
• PDBsum: 7zjw
• PubMed: 35709277
• UniProt: Q76N24|RS4X_CHLAE Small ribosomal subunit protein eS4 (Gene Name=RPS4X)