Structure of PDB 8fkx Chain SM

Receptor sequence
>8fkxSM (length=441) Species: 9606 (Homo sapiens) [Search protein sequence]
SATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHTFYLIKDIRFLL
HEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIIKERY
PTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIA
ARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFT
EFYTTLLGFVNFRLYQLLNLHYPPKLEGQGTYALDSESCMEKLAALSASL
ARVVVSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFG
GEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDS
VNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGREK
YLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKAR
3D structure
PDB8fkx Principles of human pre-60 S biogenesis.
ChainSM
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0008283 cell population proliferation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0016020 membrane
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fkx, PDBe:8fkx, PDBj:8fkx
PDBsum8fkx
PubMed37410842
UniProtO00541|PESC_HUMAN Pescadillo homolog (Gene Name=PES1)

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