Structure of PDB 8fkv Chain SM

Receptor sequence
>8fkvSM (length=453) Species: 9606 (Homo sapiens) [Search protein sequence]
SATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAAR
TFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKP
NYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCR
RLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHP
TDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLEGQGTYALDSES
CMEKLAALSASLARVVVSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVP
REALAFIIRSFGGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIG
RCYVQPQWVFDSVNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEK
LKLLALQRGREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAK
KAR
3D structure
PDB8fkv Principles of human pre-60 S biogenesis.
ChainSM
Resolution2.47 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0008283 cell population proliferation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0016020 membrane
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fkv, PDBe:8fkv, PDBj:8fkv
PDBsum8fkv
PubMed37410842
UniProtO00541|PESC_HUMAN Pescadillo homolog (Gene Name=PES1)

[Back to BioLiP]