Structure of PDB 7mq8 Chain SL

Receptor sequence
>7mq8SL (length=192) Species: 9606 (Homo sapiens) [Search protein sequence]
TRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLF
FQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCV
MAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYI
VATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF
3D structure
PDB7mq8 Nucleolar maturation of the human small subunit processome.
ChainSL
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SL S18 K35 S12 K29
BS02 rna SL R46 F78 R166 R167 K170 F198 R40 F72 R160 R161 K164 F192
BS03 rna SL R8 Y10 R15 Q22 R2 Y4 R9 Q16
BS04 ZN SL C105 C134 C144 C99 C128 C138
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome

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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9Y324|FCF1_HUMAN rRNA-processing protein FCF1 homolog (Gene Name=FCF1)

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