Structure of PDB 8yop Chain SK

Receptor sequence
>8yopSK (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQ
SLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLR
3D structure
PDB8yop Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSK
Resolution2.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SK M1 L2 M3 K25 K47 Q50 S51 S54 R55 F62 F67 M1 L2 M3 K25 K47 Q50 S51 S54 R55 F62 F67
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8yop, PDBe:8yop, PDBj:8yop
PDBsum8yop
PubMed38942792
UniProtP46783|RS10_HUMAN Small ribosomal subunit protein eS10 (Gene Name=RPS10)

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