Structure of PDB 7mqa Chain SK

Receptor sequence
>7mqaSK (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
RRLIVVLEGASLETVKVGKTYELLNCDKHKSILLKNGRDPGEARPDITHQ
SLLMLMDSPLNRAGLLQVYIHTQKNVLIEVNPQTRIPRTFDRFCGLMVQL
LHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKVGTSFSIPVVSDVRELV
PSSDPIVFVVGAFAHGKVSVEYTEKMVSISNYPLSAALTCAKLTTAFEEV
WGVI
3D structure
PDB7mqa Nucleolar maturation of the human small subunit processome.
ChainSK
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SK K56 Y61 N115 H142 L144 K154 K160 K16 Y21 N75 H102 L104 K114 K120
BS02 SAH SK T176 S177 F178 G201 F203 A204 G206 I219 S220 Y222 L224 T136 S137 F138 G161 F163 A164 G166 I179 S180 Y182 L184
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0019843 rRNA binding
GO:0042802 identical protein binding
GO:0070037 rRNA (pseudouridine) methyltransferase activity
Biological Process
GO:0001824 blastocyst development
GO:0006364 rRNA processing
GO:0017126 nucleologenesis
GO:0032259 methylation
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:0070475 rRNA base methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ92979|NEP1_HUMAN Ribosomal RNA small subunit methyltransferase NEP1 (Gene Name=EMG1)

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