Structure of PDB 7mq9 Chain SK

Receptor sequence
>7mq9SK (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
RRLIVVLEGASLETVKVGKTYELLNCDKHKSILLKNGRDPGEARPDITHQ
SLLMLMDSPLNRAGLLQVYIHTQKNVLIEVNPQTRIPRTFDRFCGLMVQL
LHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKVGTSFSIPVVSDVRELV
PSSDPIVFVVGAFAHGKVSVEYTEKMVSISNYPLSAALTCAKLTTAFEEV
WGVI
3D structure
PDB7mq9 Nucleolar maturation of the human small subunit processome.
ChainSK
Resolution3.87 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SK N115 N161 N75 N121
BS02 SAH SK T176 S177 F178 G201 F203 G206 I219 L224 K232 T136 S137 F138 G161 F163 G166 I179 L184 K192
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0019843 rRNA binding
GO:0042802 identical protein binding
GO:0070037 rRNA (pseudouridine) methyltransferase activity
Biological Process
GO:0001824 blastocyst development
GO:0006364 rRNA processing
GO:0017126 nucleologenesis
GO:0032259 methylation
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:0070475 rRNA base methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0032040 small-subunit processome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtQ92979|NEP1_HUMAN Ribosomal RNA small subunit methyltransferase NEP1 (Gene Name=EMG1)

[Back to BioLiP]