Structure of PDB 8k2a Chain SJ

Receptor sequence
>8k2aSJ (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
PVVTISDEPDILYKRLSVLVKGHDKAVLDSYEYFAVLAAKELGISIKVHE
PPRKIERFTLLQSVHIYKKHRVQYEMRTLYRCLELEHLTGSTADVYLEYI
QRNLPEGVAMEVTKTQLEQLPE
3D structure
PDB8k2a Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSJ
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SJ R113 T119 L120 L121 Q122 S123 V124 H125 I126 Y127 K128 H130 R131 Q133 R137 R53 T59 L60 L61 Q62 S63 V64 H65 I66 Y67 K68 H70 R71 Q73 R77
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8k2a, PDBe:8k2a, PDBj:8k2a
PDBsum8k2a
PubMed38942792
UniProtP82664|RT10_HUMAN Small ribosomal subunit protein uS10m (Gene Name=MRPS10)

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