Structure of PDB 8fld Chain SI

Receptor sequence
>8fldSI (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
PLVPENLLKKRKAYQALKATQAKQALLAKKEQKKGRFKRLESFLHDSWRQ
KRDKVRLRRLEVKPHALELPDKHSLAFVVRIERIDGVSLLVQRTIARLRL
KKIFSGVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKN
KTIPLTDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLS
VARHATKNRVGFLKEMGTPGYRGERINQLIRQLN
3D structure
PDB8fld Principles of human pre-60S biogenesis
ChainSI
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SI R57 F58 R60 R36 F37 R39
BS02 rna SI K51 L65 H66 W69 R70 R73 R79 R80 K84 P85 H86 R101 R104 V222 A223 R224 T227 K228 R230 K33 L44 H45 W48 R49 R52 R58 R59 K63 P64 H65 R80 R83 V201 A202 R203 T206 K207 R209
BS03 rna SI Q39 K47 K123 A223 R224 H225 Q21 K29 K102 A202 R203 H204
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8fld, PDBe:8fld, PDBj:8fld
PDBsum8fld
PubMed37410842
UniProtQ6DKI1|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)

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